NOD1 Polyclonal Antibody

This gene encodes a member of the NOD (nucleotide-binding oligomerization domain) family. This member is a cytosolic protein. It contains an N-terminal caspase recruitment domain (CARD), a centrally located nucleotide-binding domain (NBD), and 10 tandem leucine-rich repeats (LRRs) in its C terminus. The CARD is involved in apoptotic signaling, LRRs participate in protein-protein interactions, and mutations in the NBD may affect the process of oligomerization and subsequent function of the LRR domain. This protein is an intracellular pattern-recognition receptor (PRR) that initiates inflammation in response to a subset of bacteria through the detection of bacterial diaminopimelic acid.

CARD 4, CARD4, Caspase recruitment domain 4, Caspase recruitment domain containing protein 4, Caspase recruitment domain family member 4, Caspase recruitment domain protein 4, Caspase recruitment domain-containing protein 4, CLR 7.1, CLR7.1, NLR family CARD domain