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NOD2 Polyclonal Antibody

This is a NOD2 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

Product Specifications

Background

This gene is a member of the Nod1/Apaf-1 family and encodes a protein with two caspase recruitment (CARD) domains and six leucine-rich repeats (LRRs) . The protein is primarily expressed in the peripheral blood leukocytes. It plays a role in the immune response to intracellular bacterial lipopolysaccharides (LPS) by recognizing the muramyl dipeptide (MDP) derived from them and activating the NFKB protein. Mutations in this gene have been associated with Crohn disease and Blau syndrome.

Synonyms

ACUG, Arthrocutaneouveal granulomatosis, BLAU, CARD15, Caspase recruitment domain family, member 15, Caspase recruitment domain protein 15, Caspase recruitment domain-containing protein 15, CD, CLR16.3, IBD1, Inflammatory bowel disease protein 1, LRR containing prote

Swiss Prot

Q9HC29

Accession Number

NP_071445

Reactivity

Human

Immunogen

Synthetic peptide of human NOD2

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Polyclonal Antibody

Applications

IHC, ELISA

Purification Method

Affinity purification

Assay Type

Antibody

Concentration

0.8 mg/mL

Dilution

IHC 1:50-1:200

Buffer

PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Storage Conditions

Store at -20°C. Avoid freeze / thaw cycles.

Host or Source

Rabbit

Isotype

IgG

Available Sizes

Curated Selection

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