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LIN28B Polyclonal Antibody

This is a LIN28B Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

Product Specifications

Background

The protein encoded by this gene belongs to the lin-28 family, which is characterized by the presence of a cold-shock domain and a pair of CCHC zinc finger domains. This gene is highly expressed in testis, fetal liver, placenta, and in primary human tumors and cancer cell lines. It is negatively regulated by microRNAs that target sites in the 3' UTR, and overexpression of this gene in primary tumors is linked to the repression of let-7 family of microRNAs and derepression of let-7 targets, which facilitates cellular transformation. [provided by RefSeq, Jun 2012]

Synonyms

CSDD 2, CSDD2, FLJ16517, Lin 28 homolog B (C. elegans), Lin 28.2, Lin-28B, LIN28B, LN28B, Protein lin-28 homolog B

Swiss Prot

Q6ZN17

Accession Number

NP_001004317

Reactivity

Human, Mouse

Immunogen

Synthetic peptide of human LIN28B

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Polyclonal Antibody

Applications

WB, ELISA

Purification Method

Affinity purification

Assay Type

Antibody

Concentration

0.3 mg/mL

Dilution

WB 1:500-1:2000

Buffer

PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Storage Conditions

Store at -20°C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

27 kDa

Host or Source

Rabbit

Isotype

IgG

Available Sizes

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