HTRA3 Polyclonal Antibody
This is a HTRA3 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
HtrA3, also known as PRSP (pregnancy-related serine protease), is a 453 amino acid secreted protein that contains one PDZ domain, one Kazal-like domain and one IGFBP N-terminal domain. Widely expressed with particularly high expression in ovary, heart, placenta and bladder, HtrA3 functions as a probable serine protease that is thought to play an important role in placental development. HtrA3 is downregulated in ovarian tumors, suggesting an alternative role in tumor suppression. HtrA3 exists as two alternatively spliced isoforms, designated short and long. The gene encoding HtrA3 maps to human chromosome 4, which encodes nearly 6% of the human genome and has the largest gene deserts (regions of the genome with no protein encoding genes) of all of the human chromosomes.
Synonyms
High temperature requirement factor A3, High-temperature requirement factor A3, HtrA serine peptidase 3, HTRA3, HTRA3, Pregnancy related serine protease, Pregnancy-related serine protease, Probable serine protease HTRA3, PRSP, Serine protease HTRA3, Tasp
Swiss Prot
P83110
Accession Number
NP_444272
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide of human HTRA3
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
IHC, ELISA
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
0.2 mg/mL
Dilution
IHC 1:50-1:200
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Host or Source
Rabbit
Isotype
IgG
Available Sizes
Curated Selection
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