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TEK Polyclonal Antibody

This is a TEK Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

Product Specifications

Background

The TEK receptor tyrosine kinase is expressed almost exclusively in endothelial cells in mice, rats, and humans. This receptor possesses a unique extracellular domain containing 2 immunoglobulin-like loops separated by 3 epidermal growth factor-like repeats that are connected to 3 fibronectin type III-like repeats. The ligand for the receptor is angiopoietin-1. Defects in TEK are associated with inherited venous malformations; the TEK signaling pathway appears to be critical for endothelial cell-smootHuman, Mouseuscle cell communication in venous morphogenesis. TEK is closely related to the TIE receptor tyrosine kinase.

Synonyms

Angiopoietin 1 receptor, Angiopoietin-1 receptor, CD202b, CD202b antigen, Endothelial tyrosine kinase, Endothelium specific receptor tyrosine kinase 2, hTIE 2, hTIE2, Hyk, p140 TEK, Soluble TIE2 variant 1, Soluble TIE2 variant 2, Tek, tek tyrosine kinase, TEK tyrosine

Swiss Prot

Q02763

Accession Number

NP_000450

Reactivity

Human, Mouse

Immunogen

Synthetic peptide of human TEK

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Polyclonal Antibody

Applications

IHC, ELISA

Purification Method

Affinity purification

Assay Type

Antibody

Concentration

0.3 mg/mL

Dilution

IHC 1:50-1:200

Buffer

PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Storage Conditions

Store at -20°C. Avoid freeze / thaw cycles.

Host or Source

Rabbit

Isotype

IgG

Available Sizes

Curated Selection

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