PLAT Polyclonal Antibody
This is a PLAT Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
This gene encodes tissue-type plasminogen activator, a secreted serine protease which converts the proenzyme plasminogen to plasmin, a fibrinolytic enzyme. Tissue-type plasminogen activator is synthesized as a single chain which is cleaved by plasmin to a two chain disulfide linked protein. This enzyme plays a role in cell migration and tissue remodeling. Increased enzymatic activity causes hyperfibrinolysis, which manifests as excessive bleeding; decreased activity leads to hypofibrinolysis which can result in thrombosis or embolism. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms.
Synonyms
Alteplase, DKFZp686I03148, Plasminogen activator tissue, Plasminogen activator tissue type, PLAT, Reteplase, t PA, T Plasminogen Activator, t-PA, T-plasminogen activator, Tissue plasminogen activator (t PA), Tissue type plasminogen activator, Tissue-type plasminogen
Swiss Prot
P00750
Accession Number
NP_000921
Reactivity
Human
Immunogen
Synthetic peptide of human PLAT
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB, IHC, ELISA
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
0.4 mg/mL
Dilution
WB 1:200-1:1000, IHC 1:50-1:200
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
63 kDa
Host or Source
Rabbit
Isotype
IgG
Available Sizes
Curated Selection
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