SCN11A Polyclonal Antibody
This is a SCN11A Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
Voltage-gated sodium channels are membrane protein complexes that play a fundamental role in the rising phase of the action potential in most excitable cells. Alpha subunits, such as SCN11A, mediate voltage-dependent gating and conductance, while auxiliary beta subunits regulate the kinetic properties of the channel and facilitate membrane localization of the complex. Aberrant expression patterns or mutations of alpha subunits underlie a number of disorders. Each alpha subunit consists of 4 domains connected by 3 intracellular loops; each domain consists of 6 transmembrane segments and intra- and extracellular linkers.
Synonyms
HNaN, NaN, NAV1.9, Peripheral nerve sodium channel 5, PN 5, PN5, SCN 11A, SCN 12A, Scn11a, SCN12A, SCNBA, Sensory neuron sodium channel 2, SNS 2, SNS2, Sodium channel protein type 11 subunit alpha, Sodium channel protein type XI subunit alpha, Sodium channel voltage gate
Swiss Prot
Q9UI33
Accession Number
NP_054858.2
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide of human SCN11A
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
IHC, ELISA
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
0.3 mg/mL
Dilution
IHC 1:50-1:200
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Host or Source
Rabbit
Isotype
IgG
Available Sizes
Curated Selection
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