PTN Polyclonal Antibody
This is a PTN Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
Pleiotrophin (PTN) also known asheparin-binding brain mitogen (HBBM) orheparin-binding growth factor 8 (HBGF-8) orneurite growth-promoting factor 1 (NEGF1) orheparin affinity regulatory peptide (HARP) orheparin binding growth associated molecule (HB-GAM) is aproteinthat in humans is encoded by thePTNgene.Pleiotrophin is an 18-kDagrowth factorthat has a high affinity forheparin. It is structurally related tomidkineandretinoic acid induced heparin-binding protein. Secreted growth factor that induces neurite outgrowth and which is mitogenic for fibroblasts, epithelial, and endothelial cells. Binds anaplastic lymphoma kinase (ALK) which induces MAPK pathway activation, an important step in the anti-apoptotic signaling of PTN and regulation of cell proliferation.
Synonyms
HARP, HB-GAM, HBBM, HBGAM, HBGF-8, HBGF8, HBNF, HBNF-1, HBNF1, heparin affin regulatory protein, Heparin binding growth associated molecule, Heparin binding growth factor 8, Heparin binding neurite outgrowth promoting factor 1, Heparin-binding brain mitogen, Heparin-bi
Swiss Prot
P21246
Accession Number
NP_002816
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide of human PTN
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB, ELISA
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
0.3 mg/mL
Dilution
WB 1:500-1:2000
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
19 kDa
Host or Source
Rabbit
Isotype
IgG
Available Sizes
Curated Selection
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