SMG8 Polyclonal Antibody
This is a SMG8 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons. Is recruited by release factors to stalled ribosomes together with SMG1 and SMG9 (forming the SMG1C protein kinase complex) and, in the SMG1C complex, is required to mediate the recruitment of SMG1 to the ribosome:SURF complex and to suppress SMG1 kinase activity until the ribosome:SURF complex locates the exon junction complex (EJC) . Acts as a regulator of kinase activity.
Synonyms
ABC 2, ABC2, Amplified in breast cancer gene 2 protein, Chromosome 17 open reading, chromosome 17 open reading frame 71, FLJ10587, Protein smg 8 homolog, protein SMG8, SMG8, SMG8 protein
Swiss Prot
Q8ND04
Accession Number
NP_060619
Reactivity
Human, Mouse
Immunogen
Synthetic peptide of human SMG8
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
IHC, ELISA
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
0.3 mg/mL
Dilution
IHC 1:25-1:100
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Host or Source
Rabbit
Isotype
IgG
Available Sizes
Frequently Asked Questions
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