ABCD4 Polyclonal Antibody

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White) . This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. The function of this peroxisomal membrane protein is unknown. However, it is speculated that it may function as a heterodimer for another peroxisomal ABC transporter and, therefore, may modify the adrenoleukodystrophy phenotype. It may also play a role in the process of peroxisome biogenesis.

69 kDa peroxisomal ABC transporter, ABC 41, ABC41, ABCD 4, ABCD4, ABCD4, ATP binding cassette sub family D (ALD) member 4, ATP binding cassette sub family D member 4, ATP-binding cassette sub-family D member 4, EST352188, MAHCJ, MGC105956, P70R, P79R, Peroxisomal membr