PFN2 Polyclonal Antibody
This is a PFN2 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
The protein encoded by this gene is a ubiquitous actin monomer-binding protein belonging to the profilin family. It is thought to regulate actin polymerization in response to extracellular signals. There are two alternatively spliced transcript variants encoding different isoforms described for this gene. Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG.
Synonyms
D3S1319E, PFL, PFN 2, Pfn2, PROF2, Profilin II, Profilin-2, Profilin2, ProfilinII
Swiss Prot
P35080
Accession Number
NP_444252
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide of human PFN2
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB, IHC, ELISA
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
0.3 mg/mL
Dilution
WB 1:500-1:2000, IHC 1:25-1:100
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
15 kDa
Host or Source
Rabbit
Isotype
IgG
Available Sizes
Curated Selection
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