PLPP1 Polyclonal Antibody

The protein encoded by this gene is a member of the phosphatidic acid phosphatase (PAP) family. PAPs convert phosphatidic acid to diacylglycerol, and function in de novo synthesis of glycerolipids as well as in receptor-activated signal transduction mediated by phospholipase D. This protein is an integral membrane glycoprotein, and has been shown to be a surface enzyme that plays an active role in the hydrolysis and uptake of lipids from extracellular space. The expression of this gene is found to be regulated by androgen in a prostatic adenocarcinoma cell line. At least two alternatively spliced transcript variants encoding distinct isoforms have been described.

Lipid phosphate phosphohydrolase 1, Lipid phosphate phosphohydrolase 1a, LLP1a, LPP1, LPP1, PAP 2a, PAP-2a, PAP2, PAP2-alpha, PAP2a, PAP2a2, PAP2alpha2, PAPalpha1, Phosphatidate phosphohydrolase type 2a, Phosphatidic acid phosphatase 2a, Phosphatidic acid phosphatase ty