NCOR1 Polyclonal Antibody

This gene encodes a protein that mediates ligand-independent transcription repression of thyroid-hormone and retinoic-acid receptors by promoting chromatin condensation and preventing access of the transcription machinery. It is part of a complex which also includes histone deacetylases and transcriptional regulators similar to the yeast protein Sin3p. This gene is located between the Charcot-Marie-Tooth and Smith-Magenis syndrome critical regions on chromosome 17. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 17 and 20.

HN CoR, hNCoR, KIAA1047, N CoR, N Cor/SMRT corepressor Rip13, N CoR1, N-CoR, N-CoR1, NCOR 1, NCoR, Ncor1, NCOR1, Nuclear receptor co repressor 1, Nuclear receptor corepressor 1, Retinoid X receptor interacting protein 13, RIP13, Rxrip13, thyroid hormone and retinoic acid