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FAK Polyclonal Antibody

This is a FAK Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

Product Specifications

Background

This gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal transduction pathways triggered in response to certain neural peptides or to cell interactions with the extracellular matrix. Several transcript variants encoding different isoforms have been found for this gene, but the full-length natures of only three of them have been determined.

Synonyms

FADK 1, FADK, FAK related non kinase polypeptide, FAK1, FAK1, Focal adhesion kinase 1, Focal adhesion Kinase, Focal adhesion kinase isoform FAK Del33, Focal adhesion kinase related nonkinase, FRNK, p125FAK, pp125FAK, PPP1R71, Protein phosphatase 1 regulatory subunit 7

Swiss Prot

Q05397

Accession Number

NP_722560

Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide of human PTK2

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Polyclonal Antibody

Applications

WB, IHC, ELISA

Purification Method

Affinity purification

Assay Type

Antibody

Concentration

1.2 mg/mL

Dilution

WB 1:2000-1:5000, IHC 1:100-1:300

Buffer

PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Storage Conditions

Store at -20°C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

114 kDa

Host or Source

Rabbit

Isotype

IgG

Available Sizes

Curated Selection

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