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CRMP1 Polyclonal Antibody

This is a CRMP1 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

Product Specifications

Background

Collapsin response mediator protein 1, encoded by theCRMP1gene, is a humanproteinof theCRMP family. This gene encodes a member of a family of cytosolic phosphoproteins expressed exclusively in the nervous system. The encoded protein is thought to be a part of the semaphorin signal transduction pathway implicated in semaphorin-induced growth cone collapse during neural development. Alternative splicing results in multiple transcript variants. CRMP1 mediates reelin signaling in cortical neuronal migration. Mice deficient in CRMP1 exhibit impaired long-term potentiation and impaired spatial learning and memory. CRMP1 gene overlaps with another gene called EVC. CRMP1 has been shown to interact with DPYSL2.

Synonyms

Collapsin response mediator protein 1, CRMP 1, CRMP-1, Crmp1, Dihydropyrimidinase like 1, Dihydropyrimidinase related protein 1, Dihydropyrimidinase-related protein 1, DPYL1, DPYSL1, DRP 1, DRP-1, DRP1, ULIP-3, Ulip3, Unc-33-like phosphoprotein 3

Swiss Prot

Q14194

Accession Number

NP_001304

Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide of human CRMP1

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Polyclonal Antibody

Applications

WB, ELISA

Purification Method

Affinity purification

Assay Type

Antibody

Concentration

0.4 mg/mL

Dilution

WB 1:500-1:1000

Buffer

PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Storage Conditions

Store at -20°C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

62 kDa

Host or Source

Rabbit

Isotype

IgG

Available Sizes

Curated Selection

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