Benzarone
Benzarone is an oral inhibitor of human urate transporter 1 (hURAT1) with an IC50 value of 2.8 μM, and it also acts as an uncoupler of oxidative phosphorylation. Benzarone can cause liver damage and promote cell apoptosis and necrosis. Benzarone can be used to lower serum uric acid levels and for research in vascular diseases[1][2][3].
Product Specifications
CAS Number
1477-19-6
UNSPSC
12352005
Hazard Statement
H302, H413
Target
Apoptosis; Oxidative Phosphorylation; URAT1
Type
Reference compound
Related Pathways
Apoptosis; Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/benzarone.html
Purity
99.68
Solubility
DMSO : ≥ 100 mg/mL
Smiles
CCC1=C(C(C2=CC=C(O)C=C2)=O)C3=CC=CC=C3O1
Molecular Formula
C17H14O3
Molecular Weight
266.29
Precautions
H302, H413
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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