PPP1R12A Polyclonal Antibody
This is a PPP1R12A Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
Myosin phosphatase target subunit 1, which is also called the myosin-binding subunit of myosin phosphatase, is one of the subunits of myosin phosphatase. Myosin phosphatase regulates the interaction of actin and myosin downstream of the guanosine triphosphatase Rho. The small guanosine triphosphatase Rho is implicated in myosin light chain (MLC) phosphorylation, which results in contraction of smooth muscle and interaction of actin and myosin in nonmuscle cells. The guanosine triphosphate (GTP) -bound, active form of RhoA (GTP.RhoA) specifically interacted with the myosin-binding subunit (MBS) of myosin phosphatase, which regulates the extent of phosphorylation of MLC.
Synonyms
M130, MBS, Myosin binding subunit, Myosin phosphatase target subunit 1, Myosin phosphatase targeting subunit 1, Myosin phosphatase-targeting subunit 1, MYPT1, MYPT1, PPP1R12A, Protein phosphatase 1 regulatory inhibitor subunit 12A, Protein phosphatase 1 regulatory
Swiss Prot
O14974
Accession Number
BC111752
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein of human PPP1R12A
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB, ELISA
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
0.4 mg/mL
Dilution
WB 1:200-1:1000
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
115 kDa
Host or Source
Rabbit
Isotype
IgG
Available Sizes
Curated Selection
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