HSD3B7 Polyclonal Antibody

This gene encodes an enzyme which is involved in the initial stages of the synthesis of bile acids from cholesterol and a member of the short-chain dehydrogenase/reductase superfamily. The encoded protein is a membrane-associated endoplasmic reticulum protein which is active against 7-alpha hydrosylated sterol substrates. Mutations in this gene are associated with a congenital bile acid synthesis defect which leads to neonatal cholestasis, a form of progressive liver disease. Multiple transcript variants encoding different isoforms have been found for this gene.

3 beta HSD VII,3 beta hydroxy Delta (5) C27 steroid oxidoreductase,3 beta hydroxysteroid dehydrogenase type 7,3 beta hydroxysteroid dehydrogenase type VII, AI195443, BB098564, C (27) 3 beta HSD, Cca2, Cholest 5 ene 3 beta,7 alpha diol 3 beta dehydrogenase, Conflu