FAM3B Polyclonal Antibody
This is a FAM3B Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
FAM3B (family with sequence similarity 3, member B), also known as ORF9, C21orf11 or PANDER, is a 235 amino acid secreted protein that localizes to discrete vesicular and perinuclear structures. Expressed at high levels in pancreas and at lower levels in kidney, colon, testis, prostate and small intestine, FAM3B functions as an islet-specific cytokine that promotes apoptosis and may inhibit Insulin secretion from beta-cells, possibly playing a role in overall pancreatic activity. Human FAM3B shares 78% sequence identity with its mouse counterpart, suggesting a conserved role between species. Three isoforms of FAM3B, designated A, B and C, exist due to alternative splicing events. The gene encoding FAM3B maps to human chromosome 21, which houses approximately 300 genes and comprises nearly 1.5% of the human genome.
Synonyms
2-21, C21orf11, C21orf76, Cytokine like protein 2 21, Cytokine-like protein 2-21, Fam3b, FAM3B, Family with sequence similarity 3 member B, ORF9, Pancreatic-derived factor, PANDER, PRED44, Protein FAM3B
Swiss Prot
P58499
Accession Number
BC057829
Reactivity
Human, Mouse
Immunogen
Recombinant protein of human FAM3B
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
IHC, ELISA
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
0.7 mg/mL
Dilution
IHC 1:50-1:200
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Host or Source
Rabbit
Isotype
IgG
Available Sizes
Curated Selection
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