BCL10 Polyclonal Antibody

This gene was identified by its translocation in a case of mucosa-associated lymphoid tissue (MALT) lymphoma. The protein encoded by this gene contains a caspase recruitment domain (CARD), and has been shown to induce apoptosis and to activate NF-kappaB. This protein is reported to interact with other CARD domain containing proteins including CARD9, 10, 11 and 14, which are thought to function as upstream regulators in NF-kappaB signaling. This protein is found to form a complex with MALT1, a protein encoded by another gene known to be translocated in MALT lymphoma.

AI132454, B cell CLL/lymphoma 10, B cell lymphoma/leukemia10, B-cell CLL/lymphoma 10, B-cell leukemia/lymphoma 10, B-cell lymphoma/leukemia 10, Bcl 10, Bcl-10, Bcl10, BCL10, c E10, c-E10, C81403, CARD containing apoptotic signaling protein, CARD containing molecule enh