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CBR1 Polyclonal Antibody

This is a CBR1 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

Product Specifications

Background

Carbonyl reductase is one of several monomeric, NADPH-dependent oxidoreductases having wide specificity for carbonyl compounds. This enzyme is widely distributed in human tissues. Another carbonyl reductase gene, CRB3, lies close to this gene on chromosome 21q. NADPH-dependent reductase with broad substrate specificity. Catalyzes the reduction of a wide variety of carbonyl compounds including quinones, prostaglandins, menadione, plus various xenobiotics. Catalyzes the reduction of the antitumor anthracyclines doxorubicin and daunorubicin to the cardiotoxic compounds doxorubicinol and daunorubicinol.

Synonyms

15 hydroxyprostaglandin dehydrogenase [NADP+],15-hydroxyprostaglandin dehydrogenase [NADP+], Carbonyl reductase [NADPH] 1, Carbonyl Reductase 1, CBR 1, CBR1, CBR1, CRN, NADPH dependent carbonyl reductase 1, NADPH-dependent carbonyl reductase 1, Prostaglandin 9 ket

Swiss Prot

P16152

Accession Number

BC002511

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human CBR1

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Polyclonal Antibody

Applications

WB, IHC, ELISA

Purification Method

Affinity purification

Assay Type

Antibody

Concentration

0.3 mg/mL

Dilution

WB 1:1000-1:5000, IHC 1:50-1:200

Buffer

PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Storage Conditions

Store at -20°C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

30 kDa

Host or Source

Rabbit

Isotype

IgG

Available Sizes

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