DOK4 Polyclonal Antibody
This is a DOK4 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
Docking protein 4is aproteinthat in humans is encoded by theDOK4gene. Dok-4 is a 326 amino acid protein that contains one PH domain and one IRS-type PTB domain and belongs to the Dok family of interacting proteins. Expressed in a variety of tissues with highest expression in liver, heart, kidney and skeletal muscle, Dok-4 plays an important role in Ret-mediated neurite outgrowth and may link Ret with downstream effectors during neuronal differentiation. Additionally, Dok-4 is thought to play a positive role in the activation of MAPK pathways and may participate in T-cell induced immune system regulation. Overexpression of Dok-4 is associated with clear cell renal cell carcinoma, suggesting a role for Dok-4 in tumorigenesis.
Synonyms
Docking protein 4, Downstream of tyrosine kinase 4, FLJ10488, insulin receptor substrate 5, IRS5
Swiss Prot
Q8TEW6
Accession Number
BC001540
Reactivity
Human, Mouse
Immunogen
Recombinant protein of human DOK4
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
IHC, ELISA
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
0.5 mg/mL
Dilution
IHC 1:50-1:200
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Host or Source
Rabbit
Isotype
IgG
Available Sizes
Curated Selection
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