MAP4K2 Polyclonal Antibody

The protein encoded by this gene is a member of the serine/threonine protein kinase family. Although this kinase is found in many tissues, its expression in lymphoid follicles is restricted to the cells of germinal centre, where it may participate in B-cell differentiation. This kinase can be activated by TNF-alpha, and has been shown to specifically activate MAP kinases. This kinase is also found to interact with TNF receptor-associated factor 2 (TRAF2), which is involved in the activation of MAP3K1/MEKK1.

B lymphocyte serine/threonine protein kinase, B lymphocyte serine/threonine-protein kinase, BL44, GC kinase, GCK, Germinal center kinase, germinal centre kinase (GC kinase), M4K2, Map4k2, MAPK/ERK kinase kinase kinase 2, MEK kinase kinase 2, MEKKK 2, Mitogen activate