ARC Polyclonal Antibody
This is a ARC Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
Arc (for activity-regulated cytoskeleton-associated protein) is a growth factor and immediate early gene that is enriched in brain. Arc mRNA and protein levels are induced by neuronal activity, which is necessary to stimulate neuroplasticity, indicating a potential role for Arc in activity-dependent changes in dendrite function. Arc expression has been detected in neuronal cell bodies and dendrites in the hippocampus, amygdala, hypothalamus, striatum and cortex. Arc has been shown to localize to the cytoskeleton of neuronal cells and appears to colocalize with F-Actin, although it may associate with an Actin-associated protein rather than directly with F-Actin. It has been shown that cocaine-stimulated neuronal activity results in increased Arc mRNA levels in striatum.
Synonyms
Activity regulated cytoskeleton associated protein, activity regulated gene 3.1 protein homolog, Activity-regulated cytoskeleton-associated protein, Activity-regulated gene 3.1 protein homolog, Arc, ARC/ARG3.1, ARC, Arg3.1
Swiss Prot
Q7LC44
Accession Number
BC012321
Reactivity
Human
Immunogen
Recombinant protein of human ARC
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
IHC, ELISA
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
0.5 mg/mL
Dilution
IHC 1:50-1:200
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Host or Source
Rabbit
Isotype
IgG
Available Sizes
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