MAP3K12 Polyclonal Antibody
This is a MAP3K12 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
This gene encodes a member of the serine/threonine protein kinase family. This kinase contains a leucine-zipper domain and is predominately expressed in neuronal cells. The phosphorylation state of this kinase in synaptic terminals was shown to be regulated by membrane depolarization via calcineurin. This kinase forms heterodimers with leucine zipper containing transcription factors, such as cAMP responsive element binding protein (CREB) and MYC, and thus may play a regulatory role in PKA or retinoic acid induced neuronal differentiation. Alternatively spliced transcript variants encoding different proteins have been described.
Synonyms
Dlk, Dual leucine zipper bearing kinase, Dual leucine zipper kinase DLK, Leucine-zipper protein kinase, M3K12, Map3k12, MAPK-upstream kinase, MEKK12, Mitogen-activated protein kinase kinase kinase 12, Mixed lineage kinase, MUK, Protein kinase MUK, ZPK, ZPKP1
Swiss Prot
Q12852
Accession Number
BC050050
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein of human MAP3K12
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
IHC, ELISA
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
0.2 mg/mL
Dilution
IHC 1:25-1:100
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Host or Source
Rabbit
Isotype
IgG
Available Sizes
Curated Selection
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