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CCDC99 Polyclonal Antibody

This is a CCDC99 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

Product Specifications

Background

Required for the localization of dynein and dynactin to the mitotic kintochore. Dynein is believed to control the initial lateral interaction between the kinetochore and spindle microtubules and to facilitate the subsequent formation of end-on kinetochore-microtubule attachments mediated by the NDC80 complex. Also required for correct spindle orientation. Does not appear to be required for the removal of spindle assembly checkpoint (SAC) proteins from the kinetochore upon bipolar spindle attachment. Interacts with KNTC1 and ZW10. These interactions appear weak and may be transient or indirect.

Synonyms

AA409762, Arsenite related gene 1 protein, Arsenite-related gene 1 protein, CCDC 99, Ccdc99, Coiled coil domain containing 99, Coiled-coil domain-containing protein 99, FLJ20364, FLJ40690, hSpindly, MGC124977, Protein Spindly, rhabdomyosarcoma antigen MU RMS 40.4A, Rh

Swiss Prot

Q96EA4

Accession Number

BC012568

Reactivity

Human, Mouse

Immunogen

Recombinant protein of human SPDL1

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Polyclonal Antibody

Applications

WB, ELISA

Purification Method

Affinity purification

Assay Type

Antibody

Concentration

0.2 mg/mL

Dilution

WB 1:500-1:2000

Buffer

PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Storage Conditions

Store at -20°C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

70/59 kDa

Host or Source

Rabbit

Isotype

IgG

Available Sizes

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