CHRNA4 Polyclonal Antibody

This gene encodes a nicotinic acetylcholine receptor, which belongs to a superfamily of ligand-gated ion channels that play a role in fast signal transmission at synapses. These pentameric receptors can bind acetylcholine, which causes an extensive change in conformation that leads to the opening of an ion-conducting channel across the plasma membrane. This protein is an integral membrane receptor subunit that can interact with either nAChR beta-2 or nAChR beta-4 to form a functional receptor. Mutations in this gene cause nocturnal frontal lobe epilepsy type 1.

A4 nicotinic receptor, Acetylcholine receptor alpha 4 neural, Acetylcholine receptor neuronal nicotinic alpha 4 subunit, ACH 4, ACH4, ACHA4, AChR, Acra 4, Acra4, Alpha4 nAChR, BFNC, Cholinergic receptor nicotinic alpha 4, Cholinergic receptor nicotinic alpha polypept