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SERPINB5 Polyclonal Antibody

This is a SERPINB5 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

Product Specifications

Background

Maspin (mammary serine protease inhibitor) also known as serpin B5 is a protein that in humans is encoded by the SERPINB5 gene.[1] This protein belongs to the serpin (serine protease inhibitor) superfamily.[1] SERPINB5 also functions as a tumor suppressor gene in epithelial cells. The expressed protein suppresses the ability of cancer cells to invade and metastasize other tissues. The protein also functions as an angiogenesis inhibitor.It blocks the growth, invasion, and metastatic properties of mammary tumors. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, it exhibits no serine protease inhibitory activity.

Synonyms

Maspin, Ovalbumin, Peptidase inhibitor 5, PI-5, PI5, protease inhibitor 5 (maspin), Protease inhibitor 5, Serine (or cysteine) peptidase inhibitor, clade B, member 5, serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 5, Serpin B5, serpin family B m

Swiss Prot

P36952

Accession Number

BC020713

Reactivity

Human, Mouse

Immunogen

Recombinant protein of human SERPINB5

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Polyclonal Antibody

Applications

WB, IHC, ELISA

Purification Method

Affinity purification

Assay Type

Antibody

Concentration

0.5 mg/mL

Dilution

WB 1:1000-1:5000, IHC 1:100-1:300

Buffer

PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Storage Conditions

Store at -20°C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

42 kDa

Host or Source

Rabbit

Isotype

IgG

Available Sizes

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