COPS5 Polyclonal Antibody
This is a COPS5 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
The protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. This protein is reported to be involved in the degradation of cyclin-dependent kinase inhibitor CDKN1B/p27Kip1. It is also known to be an coactivator that increases the specificity of JUN/AP1 transcription factors
Synonyms
38 kDa Mov34 homolog, COP9 (constitutive photomorphogenic) homolog subunit 5, COP9 constitutive photomorphogenic homolog subunit 5, COP9 signalosome complex subunit 5, COP9 signalosome subunit 5, Cop9 subunit 5, COPS 5, cops5, CSN 5, CSN5, CSN5, JAB 1, Jun activation
Swiss Prot
Q92905
Accession Number
BC001187
Reactivity
Human, Mouse
Immunogen
Recombinant protein of human COPS5
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB, IHC, ELISA
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
0.9 mg/mL
Dilution
WB 1:1000-1:5000, IHC 1:150-1:500
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
38 kDa
Host or Source
Rabbit
Isotype
IgG
Available Sizes
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