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ITGB3BP Polyclonal Antibody

This is a ITGB3BP Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

Product Specifications

Background

This gene encodes a transcriptional coregulator that binds to and enhances the activity of members of the nuclear receptor families, thyroid hormone receptors and retinoid X receptors. This protein also acts as a corepressor of NF-kappaB-dependent signaling. This protein induces apoptosis in breast cancer cells through a caspase 2-mediated signaling pathway. This protein is also a component of the centromere-specific histone H3 variant nucleosome associated complex (CENP-NAC) and may be involved in mitotic progression by recruiting the histone H3 variant CENP-A to the centromere. Alternate splicing results in multiple transcript variants.

Synonyms

Beta 3 endonexin, Beta3 endonexin, Beta3 endonexin long form, CENP R, CENPR, CENPR, Centromere protein R, endonexin, Beta-3, HSU37139, Integrin beta 3 binding protein (beta3-endonexin), Integrin beta 3 binding protein, NRIF 3, NRIF3, Nuclear receptor interacting factor

Swiss Prot

Q13352

Accession Number

BC014385

Reactivity

Human

Immunogen

Recombinant protein of human ITGB3BP

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Polyclonal Antibody

Applications

IHC, ELISA

Purification Method

Affinity purification

Assay Type

Antibody

Concentration

0.7 mg/mL

Dilution

IHC 1:50-1:200

Buffer

PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Storage Conditions

Store at -20°C. Avoid freeze / thaw cycles.

Host or Source

Rabbit

Isotype

IgG

Available Sizes

Curated Selection

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