DUSP12 Polyclonal Antibody
This is a DUSP12 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product is the human ortholog of the Saccharomyces cerevisiae YVH1 protein tyrosine phosphatase. It is localized predominantly in the nucleus, and is novel in that it contains, and is regulated by a zinc finger domain.
Synonyms
Dual specificity phosphatase 12, Dual specificity protein phosphatase 12, Dual specificity tyrosine phosphatase YVH1, DUS12, DUSP 1, DUSP 12, DUSP1, DUSP12, Serine/threonine specific protein phosphatase, TDSP4, YVH 1, YVH1, YVH1 protein tyrosine phosphatase (S. cerev
Swiss Prot
Q9UNI6
Accession Number
BC006286
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein of human DUSP12
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB, ELISA
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
0.4 mg/mL
Dilution
WB 1:200-1:1000
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
38 kDa
Host or Source
Rabbit
Isotype
IgG
Available Sizes
Curated Selection
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