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DOK1 Polyclonal Antibody

This is a DOK1 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

Product Specifications

Background

The protein encoded by this gene is part of a signal transduction pathway downstream of receptor tyrosine kinases. The encoded protein is a scaffold protein that helps form a platform for the assembly of multiprotein signaling complexes. Two transcript variants encoding different isoforms have been found for this gene. DOK1 appears to be a negative regulator of the insulin signaling pathway. Modulates integrin activation by competing with talin for the same binding site on ITGB3.

Synonyms

Docking protein 1 62kD, Docking protein 1, DOK 1, DOK1, DOK1, Downstream of tyrosine kinase 1, p62 (dok), P62DOK, pp62

Swiss Prot

Q99704

Accession Number

BC114440

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human DOK1

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Polyclonal Antibody

Applications

WB, ELISA

Purification Method

Affinity purification

Assay Type

Antibody

Concentration

0.5 mg/mL

Dilution

WB 1:500-1:2000

Buffer

PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Storage Conditions

Store at -20°C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

52 kDa

Host or Source

Rabbit

Isotype

IgG

Available Sizes

Curated Selection

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