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CRTAM Polyclonal Antibody

This is a CRTAM Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

Product Specifications

Background

The CRTAM gene is upregulated in CD4 (see MIM 186940) -positive and CD8 (see CD8A; MIM 186910) -positive T cells and encodes a type I transmembrane protein with V and C1-like Ig domains. Interaction with CADM1 promotes natural killer (NK) cell cytotoxicity and interferon-gamma (IFN-gamma) secretion by CD8+ cells in vitro as well as NK cell-mediated rejection of tumors expressing CADM3 in vivo.

Synonyms

CD355, Class I MHC restricted T cell associated molecule, Class-I MHC-restricted T-cell-associated molecule, CRTAM, CRTAM, Cytotoxic and regulatory T cell molecule, Cytotoxic and regulatory T-cell molecule

Swiss Prot

O95727

Accession Number

BC070266

Reactivity

Human

Immunogen

Recombinant protein of human CRTAM

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Polyclonal Antibody

Applications

WB, IHC, ELISA

Purification Method

Affinity purification

Assay Type

Antibody

Concentration

0.3 mg/mL

Dilution

WB 1:500-1:2000, IHC 1:50-1:200

Buffer

PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Storage Conditions

Store at -20°C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

45 kDa

Observed Molecular Weight

Refer to Figures

Host or Source

Rabbit

Isotype

IgG

Available Sizes

Curated Selection

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