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AARS2 Polyclonal Antibody

This is a AARS2 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

Product Specifications

Background

The protein encoded by this gene belongs to the class-II aminoacyl-tRNA synthetase family. Aminoacyl-tRNA synthetases play critical roles in mRNA translation by charging tRNAs with their cognate amino acids. The encoded protein is a mitochondrial enzyme that specifically aminoacylates alanyl-tRNA. Mutations in this gene are a cause of combined oxidative phosphorylation deficiency 8. Catalyzes the attachment of alanine to tRNA (Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA (Ala) . Also edits incorrectly charged tRNA (Ala) via its editing domain

Synonyms

AARS 2, AARS2, AARSL, Alanine tRNA ligase 2 mitochondrial, Alanine tRNA ligase, Alanyl tRNA synthetase 2 mitochondrial, Alanyl tRNA synthetase like, AlaRS, bA444E17.1, COXPD8, Gm89, KIAA1270, LKENP, MGC69820, MT ALARS, MTALARS, Probable alanyl tRNA synthetase mitochondri

Swiss Prot

Q5JTZ9

Accession Number

BC131728

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human AARS2

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Polyclonal Antibody

Applications

WB, IHC, ELISA

Purification Method

Affinity purification

Assay Type

Antibody

Concentration

0.4 mg/mL

Dilution

WB 1:500-1:2000, IHC 1:50-1:200

Buffer

PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Storage Conditions

Store at -20°C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

107 kDa

Host or Source

Rabbit

Isotype

IgG

Available Sizes

Curated Selection

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