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JAK3 Polyclonal Antibody

This is a JAK3 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

Product Specifications

Background

The protein encoded by this gene is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease) .

Synonyms

EC 2.7.10.2, JAK 3, JAK L, JAK-3, Jak3, JAK3 HUMAN, JAK3, JAKL, Janus kinase 3 (a protein tyrosine kinase, leukocyte), Janus kinase 3, Janus Kinase3, L JAK, L-JAK, Leukocyte janus kinase, LJAK, Protein tyrosine kinase leukocyte, Tyrosine protein kinase JAK3, Tyrosine-prote

Swiss Prot

P52333

Reactivity

Human, Mouse, Rat

Immunogen

Synthesized peptide derived from human JAK3 around the non-phosphorylation site of Tyr785.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Polyclonal Antibody

Applications

WB, IHC-p, IF, ELISA

Purification Method

Affinity purification

Assay Type

Antibody

Concentration

1 mg/mL

Dilution

WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:20000

Buffer

PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4

Storage Conditions

Store at -20°C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

125 kDa

Observed Molecular Weight

125 kDa

Host or Source

Rabbit

Isotype

IgG

Available Sizes

Curated Selection

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