SMAD2 Polyclonal Antibody
This is a SMAD2 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
Receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases. Binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and, on formation of the SMAD2/SMAD4 complex, activates transcription. May act as a tumor suppressor in colorectal carcinoma.
Synonyms
Drosophila, homolog of, MADR2, hMAD-2, HsMAD2, JV18, JV18-1, JV181, MAD, MAD homolog 2, MAD Related Protein 2, Mad-related protein 2, MADH2, MADR2, MGC22139, MGC34440, Mother against DPP homolog 2, Mothers against decapentaplegic homolog 2, Mothers against decapentaplegic
Swiss Prot
Q15796
Reactivity
Human, Mouse, Rat
Immunogen
Synthesized peptide derived from human Smad2 around the non-phosphorylation site of Ser250.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB, IHC-p, ELISA
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:20000
Buffer
PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
52 kDa
Observed Molecular Weight
52 kDa
Host or Source
Rabbit
Isotype
IgG
Available Sizes
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