NFκB-p105/p50 Polyclonal Antibody
This is a NFκB-p105/p50 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
NFkB is a pleiotropic transcription factor which is present in almost all cell types and is involved in many biological processed such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. Activated NFkB translocates into the nucleus and stimulates the expression of genes involved in a wide variety of biological functions. Inappropriate activation of NFkB has been associated with a number of inflammatory diseases while persistent inhibition of NFkB leads to inappropriate immune cell development or delayed cell growth. NFKB1 appears to have dual functions such as cytoplasmic retention of attached NF-kappa-B proteins by p105 and generation of p50 by a cotranslational processing. This antibody can bind both p105 and p50 isoforms of NFKB1.
Synonyms
DKFZp686C01211, DNA binding factor KBF1, DNA binding factor KBF1 EBP1, DNA-binding factor KBF1, EBP 1, EBP-1, EBP1, KBF1, MGC54151, nf b, NF kappa B, NF kappaB, NF kappabeta, NF kB1, NFkappaB, NFKB 1, NFKB p105, NFKB p50, Nfkb1, NFKB1, Nuclear factor kappa B DNA binding subu
Swiss Prot
P19838
Reactivity
Human, Mouse
Immunogen
Synthesized peptide derived from human NFκB-p105/p50 around the non-phosphorylation site of Ser337.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB, IHC-p, IF, ELISA
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:40000
Buffer
PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
105 kDa
Observed Molecular Weight
50,110 kDa
Host or Source
Rabbit
Isotype
IgG
Available Sizes
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