Histone H1 Polyclonal Antibody
This is a Histone H1 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
May play a key role in the control of gene expression during oogenesis and early embryogenesis, presumably through the perturbation of chromatin structure. Essential for meiotic maturation of germinal vesicle-stage oocytes. The somatic type linker histone H1c is rapidly replaced by H1oo in a donor nucleus transplanted into an oocyte. The greater mobility of H1oo as compared to H1c may contribute to this rapid replacement and increased instability of the embryonic chromatin structure. The rapid replacement of H1c with H1oo may play an important role in nuclear remodeling.
Synonyms
HIST1H1B, H1F5, Histone H1.5, Histone H1a, Histone H1b, Histone H1s-3, HIST1H1D, H1F3, Histone H1.3, Histone H1c, Histone H1s-2, HIST1H1E, H1F4, Histone H1.4, Histone H1b, Histone H1s-4
Swiss Prot
P16401, P16402, P10412
Reactivity
Human, Mouse
Immunogen
Synthesized peptide derived from human Histone H1 around the non-phosphorylation site of Thr17.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB, IHC-p, IF, ELISA
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:20000
Buffer
PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
23 kDa
Observed Molecular Weight
31 28 kDa
Host or Source
Rabbit
Isotype
IgG
Available Sizes
Curated Selection
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