Claudin 1 Polyclonal Antibody
This is a Claudin 1 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. Loss of function mutations result in neonatal ichthyosis-sclerosing cholangitis syndrome.
Synonyms
Claudin-1, Claudin1, CLD 1, CLD1, CLD1, CLDN 1, Cldn1, ILVASC, SEMP 1, SEMP1, Senescence associated epithelial membrane protein 1, Senescence associated epithelial membrane protein, Senescence-associated epithelial membrane protein
Swiss Prot
O95832
Reactivity
Human, Mouse, Rat
Immunogen
Synthesized peptide derived from the C-terminal region of human Claudin-1
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB, IHC-p, IF, ELISA
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:40000
Buffer
PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
23 kDa
Observed Molecular Weight
22 kDa
Host or Source
Rabbit
Isotype
IgG
Available Sizes
Curated Selection
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