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ABCG2 Polyclonal Antibody

This is a ABCG2 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

Product Specifications

Background

Xenobiotic transporter that may play an important role in the exclusion of xenobiotics from the brain. May be involved in brain-to-blood efflux. Appears to play a major role in the multidrug resistance phenotype of several cancer cell lines. When overexpressed, the transfected cells become resistant to mitoxantrone, daunorubicin and doxorubicin, display diminished intracellular accumulation of daunorubicin, and manifest an ATP-dependent increase in the efflux of rhodamine 123.

Synonyms

ABC transporter, ABC15, ABCG 2, ABCG2, ABCG2, ABCP, ATP binding cassette sub family G (WHITE) member 2, ATP binding cassette transporter G2, ATP-binding cassette sub-family G member 2, BCRP, BCRP1, BMDP, Breast cancer resistance protein, CD338, CDw338, CDw338 antigen, ES

Swiss Prot

Q9UNQ0

Reactivity

Human

Immunogen

Synthesized peptide derived from the Internal region of human ABCG2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Polyclonal Antibody

Applications

WB, IHC-p, ELISA

Purification Method

Affinity purification

Assay Type

Antibody

Concentration

1 mg/mL

Dilution

WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:10000

Buffer

PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4

Storage Conditions

Store at -20°C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

72 kDa

Observed Molecular Weight

72 kDa

Host or Source

Rabbit

Isotype

IgG

Available Sizes

Curated Selection

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