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Survivin Polyclonal Antibody

This is a Survivin Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

Product Specifications

Background

This gene is a member of the inhibitor of apoptosis (IAP) gene family, which encode negative regulatory proteins that prevent apoptotic cell death. IAP family members usually contain multiple baculovirus IAP repeat (BIR) domains, but this gene encodes proteins with only a single BIR domain. The encoded proteins also lack a C-terminus RING finger domain. Gene expression is high during fetal development and in most tumors, yet low in adult tissues. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Synonyms

API4, Apoptosis inhibitor 4, Apoptosis inhibitor survivin, Apoptosis inhibitor4, Baculoviral IAP repeat containing 5, Baculoviral IAP repeat containing protein 5, Baculoviral IAP repeat-containing protein 5, BIRC 5, BIRC5, BIRC5, EPR 1, IAP4, Survivin variant 3 alpha

Swiss Prot

O15392, O70201, Q9JHY7

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein corresponding to Mouse Survivin

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Polyclonal Antibody

Applications

WB, IHC

Purification Method

Affinity purification

Assay Type

Antibody

Concentration

450 μg/mL

Dilution

WB 1:500-1:2000, IHC 1:200-1:600

Buffer

PBS with 0.02% sodium azide, 1% BSA and 50% glycerol, pH7.4

Storage Conditions

Store at -20°C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

16 kDa

Observed Molecular Weight

16-18 kDa

Host or Source

Rabbit

Isotype

IgG

Available Sizes

Curated Selection

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