ACVR1, Cynomolgus (HEK293, Fc)

Product Specifications

UNSPSC Description

Activin A receptor, type I (ACVR1), also known as ALK-2, is a bone morphogenetic protein (BMP) type I receptor. ACVR1 is involved in a wide variety of biological processes, including bone, heart, cartilage, nervous, and reproductive system development and regulation[1]. ACVR1 Protein, Cynomolgus (HEK293, Fc) is produced in HEK293 cells with a C-Terminal Fc-tag. It consists of 101 amino acids (M1-E123).

Type

Recombinant Proteins

Assay Protocol

https://www.medchemexpress.com/cytokines/acvr1-protein-cynomolgus-hek293-fc.html

Purity

96.00

Smiles

DEKPKVNPKL YMCVCEGLSC GNEDHCEGQQ CFSSLSINDG FHVYQKGCFQ VYEQGKMTCK TPPSPGQAVE CCQGDWCNRN ITAQLPTKGK SFPGTQNFHL E

Molecular Weight

Approximately 42-50 kDa due to the glycosylation.

References & Citations

[1]José Antonio Valer, et al. ACVR1 Function in Health and Disease. Cells. 2019 Oct 31;8(11):1366.|[2]Jing Pang, et al. ACVR1-Fc suppresses BMP signaling and chondro-osseous differentiation in an in vitro model of Fibrodysplasia ossificans progressive. Bone. 2016 Nov;92:29-36.