ACVR1, Cynomolgus (HEK293, Fc)
Product Specifications
UNSPSC Description
Activin A receptor, type I (ACVR1), also known as ALK-2, is a bone morphogenetic protein (BMP) type I receptor. ACVR1 is involved in a wide variety of biological processes, including bone, heart, cartilage, nervous, and reproductive system development and regulation[1]. ACVR1 Protein, Cynomolgus (HEK293, Fc) is produced in HEK293 cells with a C-Terminal Fc-tag. It consists of 101 amino acids (M1-E123).
Type
Recombinant Proteins
Assay Protocol
https://www.medchemexpress.com/cytokines/acvr1-protein-cynomolgus-hek293-fc.html
Purity
96.00
Smiles
DEKPKVNPKL YMCVCEGLSC GNEDHCEGQQ CFSSLSINDG FHVYQKGCFQ VYEQGKMTCK TPPSPGQAVE CCQGDWCNRN ITAQLPTKGK SFPGTQNFHL E
Molecular Weight
Approximately 42-50 kDa due to the glycosylation.
References & Citations
[1]José Antonio Valer, et al. ACVR1 Function in Health and Disease. Cells. 2019 Oct 31;8(11):1366.|[2]Jing Pang, et al. ACVR1-Fc suppresses BMP signaling and chondro-osseous differentiation in an in vitro model of Fibrodysplasia ossificans progressive. Bone. 2016 Nov;92:29-36.
Shipping Conditions
Blue Ice
Storage Conditions
Stored at -20°C for 2 years
Available Sizes
Curated Selection
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