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CYBB Polyclonal Antibody

This is a CYBB Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

Product Specifications

Background

Cytochrome b (-245) is composed of cytochrome b alpha (CYBA) and beta (CYBB) chain. It has been proposed as a primary component of the microbicidal oxidase system of phagocytes. CYBB deficiency is one of five described biochemical defects associated with chronic granulomatous disease (CGD) . In this disorder, there is decreased activity of phagocyte NADPH oxidase; neutrophils are able to phagocytize bacteria but cannot kill them in the phagocytic vacuoles.

Synonyms

AMCBX2, CGD, CGD91-phox, CY24B, CYBB, Cytochrome b 245, beta polypeptide, Cytochrome b (558) beta chain, Cytochrome b (558) subunit beta, Cytochrome b-245 heavy chain, Cytochrome b558 subunit beta, GP91 PHOX, gp91-1, gp91-phox, GP91PHOX, Heme-binding membrane glycoprotein

Swiss Prot

Q61093

Reactivity

Mouse, Rat

Immunogen

Recombinant protein corresponding to Mouse NOX2

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Polyclonal Antibody

Applications

IHC

Purification Method

Affinity purification

Assay Type

Antibody

Concentration

270 μg/mL

Dilution

IHC 1:200-1:1000

Buffer

PBS with 0.02% sodium azide, 1% BSA and 50% glycerol, pH7.4

Storage Conditions

Store at -20°C. Avoid freeze / thaw cycles.

Host or Source

Rabbit

Isotype

IgG

Available Sizes

Frequently Asked Questions

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