ITGAV Polyclonal Antibody
This is a ITGAV Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha V subunit. This subunit associates with beta 1, beta 3, beta 5, beta 6 and beta 8 subunits. The heterodimer consisting of alpha V and beta 3 subunits is also known as the vitronectin receptor. This integrin may regulate angiogenesis and cancer progression. Alternative splicing results in multiple transcript variants. Note that the integrin alpha 5 and integrin alpha V subunits are encoded by distinct genes.
Synonyms
Antigen identified by monoclonal L230, CD 51, CD51, DKFZp686A08142, Integrin alpha five, integrin alpha V beta 3, Integrin alpha-5, integrin alpha-V, Integrin alpha-V light chain, integrin alphaVbeta3, integrin, alpha V (vitronectin receptor, alpha polypeptide, antige
Swiss Prot
P06756, P43406
Reactivity
Human, Mouse, Rat
Immunogen
KLH conjugated Synthetic peptide corresponding to Mouse Integrin alpha-V
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
IHC
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
470 μg/mL
Dilution
IHC 1:300-1:1000
Buffer
PBS with 0.02% sodium azide, 1% BSA and 50% glycerol, pH7.4
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Host or Source
Rabbit
Isotype
IgG
Available Sizes
Curated Selection
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