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PGR Polyclonal Antibody

This is a PGR Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

Product Specifications

Background

PGR, also named as NR3C3 and PR, belongs to the nuclear hormone receptor family and NR3 subfamily. The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Progesterone receptor isoform B (PRB) is involved activation of c-SRC/MAPK signaling on hormone stimulation. The ER and PR status has been used as a predictor of breast carcinoma responsiveness to endocrine therapy and as a prognostic indicator for early recurrence.

Synonyms

NR3C3, Nuclear receptor subfamily 3 group C member 3, PGR, PR, PRA, PRB, PRGR, Progesterone receptor, Progestin receptor form A, Progestin receptor form B

Swiss Prot

P06401, Q00175, Q63449

Reactivity

Human, Mouse

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse Progesterone receptor

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Polyclonal Antibody

Applications

IHC

Purification Method

Affinity purification

Assay Type

Antibody

Concentration

1.32 mg/mL

Dilution

IHC 1:200-1:800

Buffer

PBS with 0.02% sodium azide, 1% BSA and 50% glycerol, pH7.4

Storage Conditions

Store at -20°C. Avoid freeze / thaw cycles.

Host or Source

Rabbit

Isotype

IgG

Available Sizes

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