BSG Polyclonal Antibody
This is a BSG Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
BSG, also named as 5F7, Basigin, EMMPRIN, TCSF and CD147, plays pivotal roles in spermatogenesis, embryo implantation, neural network formation and tumor progression. It stimulates adjacent fibroblasts to produce matrix metalloproteinases (MMPS) .CD147 may target monocarboxylate transporters SLC16A1, SLC16A3 and SLC16A8 to plasma membranes of retinal pigment epithelium and neural retina. It seems to be a receptor for oligomannosidic glycans. CD147 is a receptor of CypA, inducing matrix metalloproteinase expression and mediating the degradation of the extracellular matrix, plays an important role in tumorigenesis and invasion in oral cancer. It has been considered as an objective and effective marker to predict invasion and prognosis in various cancers.
Synonyms
5A11 antigen,5F7, BASI, Basigin (Ok blood group), Basigin, Blood brain barrier HT7 antigen, Bsg, CD 147, CD147, CD147 antigen, Collagenase stimulatory factor, EMMPRIN, Extracellular matrix metalloproteinase inducer, Leukocyte activation antigen M6, M 6, M6, M6 leukocyte
Swiss Prot
P26453
Reactivity
Mouse, Rat
Immunogen
Recombinant Rat Basigin protein
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB, IHC
Purification Method
Antigen Affinity Purification
Assay Type
Antibody
Concentration
1 mg/mL
Dilution
WB 1:1000-1:2000 IHC 1:100-1:300
Buffer
PBS with 0.05% Proclin300 and 50% glycerol, pH7.4.
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
30 kDa,40-60 kDa
Observed Molecular Weight
30 kDa,40-60 kDa
Host or Source
Rabbit
Isotype
IgG
Available Sizes
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