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TIG1 rabbit pAb

This gene was identified as a retinoid acid (RA) receptor-responsive gene. It encodes a type 1 membrane protein. The expression of this gene is upregulated by tazarotene as well as by retinoic acid receptors. The expression of this gene is found to be downregulated in prostate cancer, which is caused by the methylation of its promoter and CpG island. Alternatively spliced transcript variant encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008],

Product Specifications

Background

This gene was identified as a retinoid acid (RA) receptor-responsive gene. It encodes a type 1 membrane protein. The expression of this gene is upregulated by tazarotene as well as by retinoic acid receptors. The expression of this gene is found to be downregulated in prostate cancer, which is caused by the methylation of its promoter and CpG island. Alternatively spliced transcript variant encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008]

Synonyms

Retinoic acid receptor responder protein 1 (RAR-responsive protein TIG1;Tazarotene-induced gene 1 protein)

Gene ID

5918

UniProt

P49788

Cellular Locus

Membrane ; Single-pass type III membrane protein.

Host

Rabbit

Species Reactivity

Human,Rat,Mouse,

Reactivity

Human; Rat; Mouse

Immunogen

Synthesized peptide derived from human TIG1

Clonality

Polyclonal

Isotype

IgG

Source

Rabbit

Applications

IHC, IF, WB

Validated Applications

IHC,IF,WB

Stability

-20°C/1 year

Concentration

1 mg/mL

Dilution

IHC-p 1:50-200, WB 1:500-2000

Molecular Weight

51kD

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES12698-1.pdf

Observed Molecular Weight

51 kD

Subcellular Location

Membrane ; Single-pass type III membrane protein .

Other Product Names

Retinoic acid receptor responder protein 1 (RAR-responsive protein TIG1; Tazarotene-induced gene 1 protein)

Gene ID (Human)

5918

SwissProt (Human)

P49788

Available Sizes

Curated Selection

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