MCM7 Polyclonal Antibody
This is a MCM7 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 6 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. Cyclin D1-dependent kinase, CDK4, is found to associate with this protein, and may regulate the binding of this protein with the tumorsuppressor protein RB1/RB. Alternatively spliced transcript variants encoding distinct isoforms have been reported.
Synonyms
CDABP0042, CDC 47, CDC47, CDC47 homolog, Cdc47, S. cerevisiae, homolog of, DNA replication licensing factor MCM7, Homolog of S. cerevisiae Cdc47, MCM 2, MCM 7, MCM2, MCM2, formerly, Mcm7, MCM7 minichromosome maintenance deficient 7, MCM7_HUMAN, Minichromosome Maintaine
Swiss Prot
P33993
Reactivity
Human
Immunogen
Recombinant Human DNA replication licensing factor MCM7 protien
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
IHC
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
2 mg/mL
Dilution
IHC 1:50-1:200
Buffer
PBS with 0.05% Proclin300 and 50% glycerol, pH7.4.
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Host or Source
Rabbit
Isotype
IgG
Available Sizes
Curated Selection
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