MGMT Polyclonal Antibody
This is a MGMT Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
Alkylating agents are potent carcinogens that can result in cell death, mutation and cancer. The protein encoded by this gene is a DNA repair protein that is involved in cellular defense against mutagenesis and toxicity from alkylating agents. The protein catalyzes transfer of methyl groups from O (6) -alkylguanine and other methylated moieties of the DNA to its own molecule, which repairs the toxic lesions. Methylation of the genes promoter has been associated with several cancer types, including colorectal cancer, lung cancer, lymphoma and glioblastoma.
Synonyms
6 O methylguanine DNA methyltransferase,6-O-methylguanine-DNA methyltransferase, Agat, AGT, AI267024, EC 2.1.1.63, Methylated DNA protein cysteine methyltransferase, Methylated-DNA--protein-cysteine methyltransferase, Methylguanine DNA methyltransferase, MGC10702
Swiss Prot
P16455
Reactivity
Human
Immunogen
Recombinant human Methylated DNA protein cysteine methyltransferase protein
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
2 mg/mL
Dilution
WB 1:500-1:1000
Buffer
PBS with 0.05% Proclin300 and 50% glycerol, pH7.4.
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
22 kDa
Observed Molecular Weight
22 kDa
Host or Source
Rabbit
Isotype
IgG
Available Sizes
Curated Selection
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